CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage
نویسندگان
چکیده
منابع مشابه
MUS81-EME2 Promotes Replication Fork Restart
Replication forks frequently stall at regions of the genome that are difficult to replicate or contain lesions that cause replication blockage. An important mechanism for the restart of a stalled fork involves endonucleolytic cleavage that can lead to fork restoration and replication progression. Here, we show that the structure-selective endonuclease MUS81-EME2 is responsible for fork cleavage...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2020
ISSN: 1469-221X,1469-3178
DOI: 10.15252/embr.201948920